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Chromatin/Epigenetics

DNA manipulation is a subcategory of signaling pathways that involves the intentional alteration of genetic material in order to study gene function, develop new treatments for genetic diseases, and create genetically modified organisms. This manipulation can be achieved through a variety of techniques such as gene editing, gene silencing, and gene transfer.

Gene editing techniques like CRISPR-Cas9 allow researchers to make precise changes to DNA sequences, enabling the correction of genetic mutations or the introduction of new genes. Gene silencing methods, such as RNA interference, can be used to temporarily or permanently turn off specific genes to study their function or prevent the expression of harmful genes.

Gene transfer techniques involve the introduction of foreign DNA into an organism’s genome, either for research purposes or to confer new traits or abilities. These tools have revolutionized the field of molecular biology and have countless applications in medicine, agriculture, and biotechnology.

Overall, DNA manipulation plays a crucial role in understanding genetic mechanisms and has the potential to shape the future of healthcare and agriculture.

Product Search

Parthenolide, N1315, C15H20O3,
CTPB, C5773, C31H43ClF3NO2, selective activator of the histone acetyltransferase (HAT) p300
AGK7, C5709, C23H13Cl2N3O2, cell-permeable, selective inhibitor of SIRT2
BRD6688, C5334, C16H18N4O, HDAC inhibitor
JFD00244, C5180, C30H26N2O4, inhibitor of SIRT2
Bizine, C5162, C18H23N3O, LSD1 inhibitor
MS37452, C5042, C22H26N2O5, competitive inhibitor of CBX7 chromodomain binding to H3K27me3
HAT Inhibitor II, C5000, C20H16Br2O3, inhibitor of the histone acetyltransferase p300
(S)-PFI-2 (hydrochloride), C4834, C23H25F4N3O3S·HCl, Negative control of (R)-PFI 2 hydrochloride
IOX4, C4672, C15H16N6O3, PHD2 inhibitor

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