RiboGrip® RNase Inhibitor (220 U/µl) is an in silico-designed protein-based ribonuclease inhibitor, which inactivates RNase A, RNase B and RNase C.
RiboGrip® inhibits the activity of ribonuclease A by noncovalently binding in a non-competitive mode at a ratio of 1:1. It is primarily used to prevent RNA degradation by contaminating RNases in various assays that use RNA sample materials, such as first strand cDNA synthesis, RT-(q)PCR, RT-LAMP, etc.
RiboGrip® also includes a genetic modification – Stability TAG – Solis BioDyne’s proprietary and patented polypeptide stabilization technology. Stability TAG makes RiboGrip® extremely tolerant to higher temperatures and enables room temperature shipping as well as effective use in assays requiring high incubation temperatures. in assays requiring high incubation temperatures. Demonstrated through our in-house testing where RiboGrip® retains full activity after 1 hour incubation at 60 °C.
Unique high concentration and glycerol free formulation is perfect for lyophilization!
Included in FIREScript® and SOLIScript® cDNA Synthesis Kits and Mixes, and in all SOLIScript® 1-step RT-PCR kits.