About

ProFoldin is a leading provider of innovative protein folding solutions and research reagents for the biotechnology, pharmaceutical, and academic research sectors. With a focus on excellence, innovation, and customer satisfaction, ProFoldin offers a diverse range of products and services aimed at advancing protein folding research and drug discovery efforts. Their commitment to quality and reliability has made them a trusted partner for scientists and researchers worldwide.

Products   

1. Chaperone Proteins:
   • Hsp70 Family: Recombinant heat shock protein 70 (Hsp70) and related co-chaperones for protein folding, stabilization, and quality control in vitro and in vivo.
   • Hsp90 Family: Recombinant heat shock protein 90 (Hsp90) and co-chaperones for chaperone-assisted protein folding, maturation, and client protein stabilization.
2. Protein Folding Assays:
   • Chaperone Activity Assays: Kits for the quantitative assessment of chaperone-mediated protein folding, refolding, and aggregation prevention in vitro.
   • Protein Misfolding Detection: Assays and reagents for the detection and quantification of misfolded proteins, protein aggregates, and amyloid fibrils.
3. Protein Engineering Tools:
   • Folding Enhancers: Small molecules, peptides, and engineered proteins designed to enhance protein folding efficiency, stability, and solubility.
   • Folding Sensors: Fluorescent and luminescent protein sensors for real-time monitoring of protein folding dynamics and kinetics.
4. Protein Quality Control Reagents:
   • Protease Inhibitors: Inhibitors of proteolytic enzymes, including proteasome inhibitors and lysosomal inhibitors, for studying protein degradation pathways and quality control mechanisms.
   • Ubiquitin Ligases: Recombinant ubiquitin ligases and ubiquitin-like proteins for studying protein ubiquitination and degradation by the ubiquitin-proteasome system.
5. Custom Protein Services:
   • Protein Expression: Custom protein expression services using bacterial, yeast, insect, or mammalian expression systems for the production of recombinant proteins, chaperones, and folding sensors.
   • Protein Purification: Purification and characterization of recombinant proteins using chromatography, affinity purification, and size-exclusion techniques.

Services 

1. Protein Folding Assay Development:
   • Development of custom protein folding assays and screening platforms for evaluating chaperone activity, protein folding kinetics, and protein stability under various conditions.
2. Protein Engineering Consulting:
   • Expert consulting services on protein engineering strategies, including rational design, directed evolution, and computational modeling, to improve protein folding and stability.
3. Technical Support and Training:
   • Expert technical support and training services to assist researchers in experimental design, protocol optimization, and data analysis for protein folding studies and assay development.

Location:

ProFoldin is headquartered in Hudson, Massachusetts, USA, with distribution centers and partners located strategically to ensure efficient shipping and support for customers worldwide.

Contact Information:

• Headquarters Address: ProFoldin, Inc., 10 Technology Drive, Suite 40, Hudson, MA 01749 USA
• Phone: +1 508-735-2539
• Email: info@profoldin.com
• Website: ProFoldin

ProFoldin is dedicated to advancing protein folding research and drug discovery by providing high-quality reagents, assays, and services to the global scientific community. Their expertise in protein folding mechanisms and chaperone biology, combined with their commitment to customer satisfaction, makes them a preferred partner for researchers seeking innovative solutions for their protein-related studies.